Principal investigator
Amaia Arranz Mendiguren
Ikerbasque Research Professor and Group Leader at Achucarro Basque Center for Neuroscience, where she leads the Laboratory of Humanized Models of Disease.
She obtained her PhD in Neuroscience from the University of the Basque Country (EHU) and conducted postdoctoral research at VIB–KU Leuven in Belgium and Sanford Burnham Prebys Medical Discovery Institute in the United States.
Her research focuses on understanding the molecular and cellular mechanisms underlying Alzheimer´s disease and neurodegeneration, with a particular emphasis on the role of human astrocytes. Her laboratory combines human iPSC-derived brain cells, human-based models and patient-derived samples, with omics technologies and functional approaches to investigate disease mechanisms and identify novel therapeutic targets.
Publications